Share your thoughts how technology can assist in increasing capacity and reducing constraints in Operations. Use examples in both service and manufacturing environments to help support your answer.


250 words or more

no double space.

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technology in operations

Share your thoughts how technology can assist in increasing capacity and reducing constraints in Operations. Use examples in both service and manufacturing environments to help support your answer.

250 words or more

no double space.

 

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I have two articles kind of lengthy but I only need you to write 300 words in a very specific format that I will attach down below.

I already choose a side of the debate I just want you to follow along and make it 300 words.

here is the debate question: Ignatieff vs de Waal – Are human rights and military action (that is, the “responsibility to protect”) ever compatible?

I have attached both articles. You just need to go over the format of the paper which is also attached and write 300 words.

thanks

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The Introduction:

Gene editing and manipulation is a newer, but rapidly growing field. We have the ability to change, add or delete genes in human embryos, adults and plants alike. We are going to explore both of these topics for this forum. You are to CHOOSE ONE of the ideas below and follow the direction.

The Objective:

Understand the methods and impacts of gene editing on humans and plants

Choice 1: Editing Human Embryos and Adults

With respect to gene editing in human embryos, most research is focused on fixing or removing harmful mutations that may cause diseases, but there are some fears of creating designer babies. In addition, we can edit the genes in adults, if we use a targeted approach. Read the articles below, and then respond to the prompt.

Pro and Con: Should Gene Editing be Performed on Human Embryos? Pro by Harris (2016) and Con by Darnovsky (2016).

https://www.nationalgeographic.com/magazine/2016/08/human-gene-editing-pro-con-opinions/

A human has been injected with gene-editing tools to cure his disabling disease. Here’s what you need to know. (Kaiser, 2017) http://www.sciencemag.org/news/2017/11/human-has-been-injected-gene-editing-tools-cure-his-disabling-disease-here-s-what-you

CRISPR fixes disease gene in viable human embryos (Ledford, 2017)

https://www.nature.com/news/crispr-fixes-disease-gene-in-viable-human-embryos-1.22382

The first CRISPR edited babies are (probably) here. Now What? From: Science Friday

https://www.sciencefriday.com/segments/the-first-crispr-edited-babies-are-probably-here-now-what/

For your original post:

  • Find a reputable resource, making sure to add an attribute or URL so that we can all view it, concerning gene editing in human embryos or adults.
  • Make sure to add a descriptive title so that others know what you are discussing.
  • Briefly summarize the main take home points of the research – make sure to include scientific terminology and discussion (remember, we are in a biology class!).
  • Some questions to consider: What is your take on the research? Are there any benefits and/or costs? Should we be focusing on this? Is there reason for concern?

Choice 2: Genetic Engineering of Plants

Genetically engineered crops are another controversial topic. They first began as a way to allow those in third world countries to grow crops that could survive in less than ideal conditions (such as drought tolerance, higher yield), and/or were higher in nutrition, meaning there was more benefit to each bite – dubbed the “Green Revolution.” You can read about it from Pingali (2012).

If you would like a little more background on genetic engineering in plants, read these resources:

Genetic engineering and GM crops (ISAAA, 2016)

http://www.isaaa.org/resources/publications/pocketk/17/default.asp

Safety of genetically engineered foods (NRC, 2004)

https://www.ncbi.nlm.nih.gov/books/NBK215771/

Genetically modified plants and human health (Key, Ma & Drake, 2008)

http://doi.org/10.1258/jrsm.2008.070372

For your original post:

  • You are to find a resource, making sure to add an attribute or URL so that we can all view it, on genetic engineering of plants. You can choose a specific plant, or discuss the generic practice of modification – but it must be different than anyone else in the class or you will not receive credit.
  • Make sure the title of your post is descriptive so that others know what you are discussing.
  • Briefly summarize the main take home points of the research – make sure you use proper scientific terminology and discussion (remember we are in a biology class).
  • Some questions to consider: Is it ethically responsible to engineer plants? Does it make a difference whether they are geared towards first or third world countries? Will they help or hinder our efforts to feed the ever-growing world population?

Resources:

Darnovsky, M. (2016). Con: Do not open the door to editing genes in future humans. National Geographic. Retrieved from https://www.nationalgeographic.com/magazine/2016/08/human-gene-editing-pro-con-opinions/

Harris, J. (2016). Pro: Research on gene editing in humans must continue. National Geographic. Retrieved from https://www.nationalgeographic.com/magazine/2016/08/human-gene-editing-pro-con-opinions/

ISAAA. (2016). Genetic Engineering and GM Crops. Pocket K No. 17. Retrieved from http://www.isaaa.org/resources/publications/pocketk/17/default.asp

Kaiser, J. (2017, Nov 15). A human has been injected with gene-editing tools to cure his disabling disease. Here’s what you need to know. Science. Retrieved from http://www.sciencemag.org/news/2017/11/human-has-been-injected-gene-editing-tools-cure-his-disabling-disease-here-s-what-you

Key, S., Ma, J. K.-C., & Drake, P. M. (2008). Genetically modified plants and human health. Journal of the Royal Society of Medicine, 101(6), 290–298. http://doi.org/10.1258/jrsm.2008.070372

Ledford, H. (2017). CRISPR fixes disease gene in viable human embryos. Nature. Retrieved from https://www.nature.com/news/crispr-fixes-disease-gene-in-viable-human-embryos-1.22382

National Research Council (US) Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health. (2004). Safety of Genetically Engineered Foods: Approaches to Assessing Unintended Health Effects. Washington (DC): National Academies Press (US). 2, Methods and Mechanisms for Genetic Manipulation of Plants, Animals, and Microorganisms. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK215771/

Pingali, P. L. (2012). Green Revolution: Impacts, limits, and the path ahead. Proceedings of the National Academy of Sciences of the United States of America, 109(31), 12302–12308. http://doi.org/10.1073/pnas.0912953109

Minimum 250 words answer

Classmate #1:

Even writing that title out seemed unethical to me, but for this week I chose to research and write about the process of editing human embryos for genetic mutations. The main article I wanted to focus on talked about the research Shoukhrat Mitalipov is doing, based out of The Oregon Health and Science Institute in Portland. Seems like he and his team have found a way to lessen the chance of “off-target mutations” happening by injecting the egg at the same time the sperm fertilizes with it. It is allowing for more precise targeting of mutations. In this article I read that the United States doesn’t allow federal funds to aid in the research of human embryos, yet if it is privately funded then it is legal. Whereas in Sweden creating human embryos for the sole purpose of research is not legal. This research that Mitalipov’s team is doing might be considered the largest examination of genome-edited human embryos, but it is recommended that more research still needs to be done in order to know with certainty that off-target mutations are not taking place during editing.

I don’t negate the pros that could come out of some scientific research such as this, there are some terrible defects or mutations that I wouldn’t wish on anyone’s child that exist in this world. Yet it still doesn’t settle with me ethically to create embryos just to perform research on them and then waste them. I do wonder and worry about the creation of “designer babies” like this article talked about. Parents who can afford to strategically choose which traits they want to retain in their embryo and which to discard. I wouldn’t trade my 4 kids for the whole world, their quirks and all, but I have been so blessed to have 4 healthy children born without any defects or complications, I wonder if I would have the same stance if I hadn’t been so blessed?

https://www.nature.com/news/crispr-fixes-disease-gene-in-viable-human-embryos-1.22382

Classmate #2:

Hello class,

A young teenager by the name of David was born with sickle cell anemia, an inherited disorder, and must undergo regular infusions for pain relief. This disease has also led to chronic and permanent damage to other organs within his body. Scientists, however, believe this potentially deadly genetic disease can be cured by deleting and repairing the mutated gene sequence of his DNA.

We’ve learned that DNA is genetically coded to make four proteins: adenosine (A), cytosine (C), guanine (G), and thymine (T), which are all arranged in a specific order. It is through this repetitive sequence of codes and patterns in DNA that CRISPR received its name: clustered regularly interspaced short palindromic repeats. In simple terms, CRISPR gene editing can be accomplished by designing the right code for a mutated gene, using enzymes, then using that code to insert the correct DNA sequence. The costs associated with gene editing is prohibitive, however, and is estimated at being more than hundreds of thousands of dollars.

One “typo” in this sequence, however, can cause a mutation or become deadly, which is where the dilemma ensues. The technology is not fail-proof; one askew gene can have serious consequences. It is the equivalent of having a single wrong letter in a book containing six billion letters. The issues can compound exponentially.

We are all likely witnessing one of the most revolutionary advancements in modern technology when it comes to gene editing. However, scientists have only scratched the surface. Despite the cutting-edge technology, I believe scientists need to continue to refine the technology through additional research before it can be used in routine practice. The technology is necessary to find solutions to eradicating incurable diseases. The question then becomes, where is the line in the sand drawn? When it comes to designing DNA for desirable traits and characteristics, the technology is misused, and it has gone too far, in my opinion.

Enjoy the week,

Stay safe,

Sean

Shwartz, M., Holley, J., & Archibald, T. (n.d.). CRISPR is a gene-editing tool that’s revolutionary, though not without risk. Retrieved March 31, 2020, from https://stanmed.stanford.edu/2018winter/CRISPR-for…

Minimum 150 words answer to each.

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Consider the following function. A(m, n) =    n + 1 if m = 0 A(m − 1, 1) if m > 0 and n = 0 A(m − 1, A(m, n − 1)) if m > 0 and n > 0 Write a recursive function to compute A(m, n) for any values of m and n.

all the details on the picture https://prnt.sc/rpumxa


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1. 2500 words

2. 15 references and use the reference I uploaded ( it is in the pdf files from unit 1- unit 6)

3.Structure

  • Appropriate coversheet (as attached in this document)
  • Title Page, including the given title in full.
  • Executive Summary 

  • Contents Page 

    • Introduction

    • Literature review to support your accounting models used. 

    • Sources of Funding 

    • Investment appraisal 

    • Cash budgeting 

    • Breakeven analysis 

    • Evaluation

    • Any other issues to be considered. 

    • Conclusions and Recommendations 

    • Appendices which should be numbered.

4. Requirement:

You will be required to write a management report to the management of Williams limited directors in which the following points should be discussed.

  • Provide an explanation on the different sources of funding the company can have and their advantages and disadvantages. You should make recommendations as to how the company can manage the same to help in the planned expansion program.
  • Analyse the Investment proposals by using NPV and provide recommendations. You should also briefly comment on other investment proposal techniques that Williams Limited may use, and the limitations of using those techniques
  • The use of management tools such as Breakeven analysis and Budgets.
  • A computation of your breakeven analysis and the cash budget for the first 3 months.
  • An evaluation of the estimated company performance or position during the same period
  • A detailed Literature Review of the tools you have used such as breakeven analysis and
  • budgets and their importance to business.
  • Other issues for management to consider that you think are vital for them to survive and make a profit.

5.Layout

  • Font style, Arial, font size 12
  • 1.5 line spacing.
  • The page orientation should be ‘portrait’
  • Margins on both sides of the page should be no less than 2.5 cm
  • Pages should be numbered
  • Your name should not appear on the script.

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  • The Assignment must be submitted in (WORD format only).
  • Students are advised to make their work clear and well presented, marks may be reduced for poor presentation.
  • Students must mention question number clearly in their answer.
  • Late submission will NOT be accepted.
  • Avoid plagiarism, the work should be in your own words, copying from students or other resources without proper referencing will result in ZERO marks. No exceptions.
  • All answered must be typed using Times New Roman (size 12, double-spaced) font. No pictures containing text will be accepted and will be considered plagiarism).
  • Citing of references is also necessary in APA style.

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Algebra quiz with about 20 questions. 2 hour time limit. Must score 100%

Questions will be posted once assigned

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Unit 4 Group DB: Common Resources and Public Goods

Select a familiar or local Common Resource or Public Good (see text for examples to consider).

  • Assess the existence of free riders, externalities, cost-benefit analysis, likelihood of a “Tragedy of the Commons” issue, etc.
  • Evaluate the controls currently in place to protect or maintain the resource/good
  • Discuss the sustainability or need for change of the current status.

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1. Answer ONE of these questions: 1A) In our opinion, which one of Franklin D. Roosevelt’s New Deal program made the most important and lasting changes to U.S. society? Using historical details from the readings or assigned videos, explain why you feel this way and discuss an example(s) in detail to support your argument. OR 1B) In your opinion, what was the least successful program, or biggest failure of the New Deal? Using historical details and examples from the readings or assigned/recommended/optional videos, explain and support your argument. Again, only pick ONE of these questions to answer. (10+ sentences. 20 points)

2. The New Deal forever changed the face and role of the federal government in American’s lives. Based on the types of programs that were ultimately sponsored by the New Deal (and compared with previous types and absences of government programs explored in this course), explain 1 major way the New Deal changed the face and role of the federal government. Explain your answer in 5+ sentences and be sure to discuss details from course materials (versus simply writing a several vague and overly general opinion sentences).

HINT 1: one idea that might help you arrive at an answer to this question is to think, what type of future federal government programs do you think the New Deal set the stage for? Only address this question if it will help you arrive at an answer to this discussion question. You’re not required to address this hint in your response. HINT 2: You could, if you wanted to, try to connect/compare/contrast the New Deal program to the coronavirus stimulus package passed by Congress this past week. I’ll include a link to this package at the end of the Week 9 module if you’d like to read more about it. HINT 3: I’m also including 2 political cartoons giving opposite viewpoints on the Great Depression in the next file. They may also be helpful for this response. With the hints, you only have to mention them if they will help you with this response.

Use your best guess. There can be multiple right answers and as long as you thoughtfully discuss accurate historical details from this week’s course materials, you will get credit for your response. I mainly wanted to encourage you to think about what long-term ramifications emerged from the New Deal. (5+ sentences, 10 points)

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